Blar i forfatter "Mizoro, Yasutaka"

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    • Circadian clock mechanism driving mammalian photoperiodism 

      Wood, Shona Hiedi; Hindle, Matthew; Mizoro, Yasutaka; Cheng, Y; Saer, Ben; Miedzinska, K; Christian, Helen; Begley, Nicola; McNeilly, Judy; McNeilly, Alan; Meddle, Simone; Burt, Dave; Loudon, Andrew S.I. (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-08-27)
      The annual photoperiod cycle provides the critical environmental cue synchronizing rhythms of life in seasonal habitats. In 1936, Bünning proposed a circadian-based coincidence timer for photoperiodic synchronization in plants. Formal studies support the universality of this so-called coincidence timer, but we lack understanding of the mechanisms involved. Here we show in mammals that long photoperiods ...

    • Immunologic Profiling of the Atlantic Salmon Gill by Single Nuclei Transcriptomics 

      West, Alexander Christopher; Mizoro, Yasutaka; Wood, Shona; Ince, Louise M.; Iversen, Marianne; Jørgensen, Even Hjalmar; Nome, Torfinn; Sandve, Simen Rød; Martin, Samuel A. M.; Loudon, Andrew S. I.; Hazlerigg, David (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-05-04)
      Anadromous salmonids begin life adapted to the freshwater environments of their natal streams before a developmental transition, known as smoltification, transforms them into marine-adapted fish. In the wild, smoltification is a photoperiod-regulated process, involving radical remodeling of gill function to cope with the profound osmotic and immunological challenges of seawater (SW) migration. While ...